The Dogon of the Bandiagara Escarpment and the Seno Plains in Central Eastern Mali have long been known to inhabit these regions for centuries. However, the history of the Dogon and Pre-Dogon settlements remained incompletely searched and maintained through myth and oral histories. This workshop brings together researchers from the Max-Planck Institute for the Science of Human History and the University of Geneva, who work jointly to uncover the history of population settlements in these regions. The workshop will focus on recent advances in the retrieval and analyses of ancient human remains and ancient pathogens. We aim to discuss recent findings from genomics, pathogenomics and biological anthropology to reveal the genetic structure of populations. Moreover, we will explore new avenues in simulation modelling to investigate population continuity in the region using ancient and modern DNA.