Dr. Irina Marie Velsko

Dr. Irina Marie Velsko

Department of Archaeogenetics
+49 3641 686-690

Main Focus

Research interests

  • Microbiome evolution

  • Oral microbiology & immunology

  • Host-microbe interactions

  • Multi-species infections

Curriculum Vitae


2010-2014 – PhD in Biomedical Sciences, University of Florida, Gainesville, FL, USA

2006-2010 – BA in Biology, University of California, Santa Barbara, Santa Barbara, CA, USA


Research Experience

2018 Sept -present Post-doctoral Research Associate; Advisor: Dr. Christina Warinner

    Max Plank Institute for the Science of Human History, Dept. of Archaeogenetics

    Project: Is being developed

2016 Dec-2018 Aug Post-doctoral Research Associate; Advisor: Dr. Vincent Richards

    Clemson University, Department of Biological Sciences

    Project: Comparative genomics of health-associated oral Streptococcus species

2015-2016 Nov Post-doctoral Research Associate; Advisors: Prof. Greger Larson, Dr. Christina Warinner

    University of Oxford, School of Archaeology, RLAHA

    Project: Investigating the effects of the Industrial Revolution on oral biology and health

2015 Jan-2015 Nov Post-doctoral Fellow; Advisor: Dr. Luciana Shaddox

    University of Florida, Department of Periodontology

    Project: Immune responses to subgingival biofilms in localized aggressive periodontitis

2010 Aug-2014 Dec Pre-doctoral Fellow; Dissertation Advisor: Dr. Kesavalu Lakshmyya

    University of Florida, Departments of Oral Biology and Periodontology

    Dissertation: Periodontal Pathogen-induced Atherosclerosis in ApoE-/- and Integrin b6-/- Mice

Selected publications

Velsko, I. M., L. A. F. Frantz, A. Herbig, G. Larson, C. Warinner. Selection of appropriate metagenome taxonomic classifiers for ancient microbiome research. mySystems. 2018, 3(4):e00080-18. https://doi.org/10.1128/ mSystems.00080-18. *Editor’s Pick. Preprint https://doi.org/10.1101/260042.

Velsko, I. M., and L. M. Shaddox. Consistent and reproducible long-term in vitro growth of health and disease-associated oral subgingival biofilms. BMC Microbiology 2018, 18(70).  https://doi.org/10.1186/s12866-018-1212-x. Preprint bioRxiv: https://doi.org/10.1101/324475.

Velsko, I. M., K. A. Overmyer, C. Speller, M. Collins, L. Loe, L. A. F. Frantz, J. B. Rodriguez Martinez, E. Chaves, L. Klaus, K. Sankaranarayanan, Cecil M. Lewis Jr., J. J. Coon, G. Larson, C. Warinner. The dental calculus metabolome in modern and historic samples. Metabolomics. 2017, 13(134). doi: 10.1007/s11306-017-1270-3. Preprint bioRxiv doi: https://doi.org/10.1101/136176

Velsko, I. M., C. Warinner. Bioarchaeology of the human microbiome. Bioarchaeology International. 2017, 1(1-2):86-99, doi: 10.5744/bi.2017.1004.   

Velsko, I. M., Y. Cruz-Almeida, H. Huang, S. Wallet, L. Shaddox. Mononuclear Cell Cytokine Response Patterns to Complex Biofilms Discriminate Biofilm Dysbiosis and Patient Disease Status. Journal of Oral Microbiology. 2017, 9(1):1330645. doi: 10.1080/20002297.2017.1330645.

Chukkapalli, S. S., I. M. Velsko, M. F. Rivera-Kweh, D. Zheng, A. R. Lucas, L. Kesavalu. Polymicrobial infection with four periodontal bacteria orchestrates a distinct inflammatory response and atherosclerosis in ApoEnull mice.  PLOS ONE. 30 November 2015, 10(11):e0143291. doi: 10.1371/journal.pone.0143291.

Velsko, I. M., S. S. Chukkapalli, M. F. Rivera-Kweh, D. Zheng, I. Aukhil, A. R. Lucas, H. Larjava, L. Kesavalu. Periodontal pathogens invade gingiva and aortic adventitia and elicit inflammasome activation in αvβ6 integrin-deficient mice. Infection and Immunity. 2015, 83(12): 4582-4593. doi: 10.1128/IAI.01077-15.

Velsko, I. M.*, S. S. Chukkapalli*, M. F. Rivera-Kweh, H. Chen, D. Zheng, I. Bhattacharyya, P. R. Gangula, A. R. Lucas, L. Kesavalu. Fusobacterium nucleatum Alters Atherosclerosis Risk Factors and Enhances Inflammatory Risk Markers with an Atheroprotective Immune Response in ApoEnull Mice. PLOS ONE. 16 June 2015, 10(6):e0129795. doi: 10.1371/journal.pone.0129795.

Velsko, I. M.*, S. Chukkapalli*, M. Rivera, J-Y. Lee, H. Chen, D. Zheng, I. Bhattacharyya, A. Lucas, and L. Kesavalu. Active invasion of oral and aortic tissues by P. gingivalis in mice causally links periodontitis and atherosclerosis. PLOS ONE. 16 May 2014, 9(5):e97811. doi: 10.1371/journal.pone.0097811.

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