Patxi Pérez Ramallo is committed to applying archaeological science methodologies such as osteology, stable isotope and aDNA, within multidisciplinary research programmes that are focused on geographical mobility, diet, pathologies and genetics, linked to religious and ritual contexts.  

Since 2015, Ramallo is the head of an interdisciplinary project about the origin and evolution of the Medieval Camino and the Cathedral of Santiago de Compostela. The Way of Saint James and the Cathedral of Santiago were declared as part of the first European Cultural Route by the Council of Europe, with both also being named as UNESCO World Heritage Sites.